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National Institutes of Health

Eunice Kennedy Shriver National Institute of Child Health and Human Development

2019 Annual Report of the Division of Intramural Research

NICHD-NIDDK-NIDCR Inter-Institute Endocrine Training Program

  • Ranganath Muniyappa, MD, PhD, Director, Inter-Institute Endocrine Training Program; Diabetes, Endocrinology, and Obesity Branch, NIDDK
  • Michael T. Collins, MD, Director, Career Development and Research Oversight, NIDCR Senior Investigator, CSDB, NIDCR
  • Fady Hannah-Shmouni, MD, FRCPC, Associate Director, Inter-Institute Endocrine Training Program, NICHD
  • Constantine Stratakis, MD, D(med)Sci, Scientific Director and Head, Section on Endocrinology and Genetics, NICHD
  • Karel Pacak, MD, PhD, DSc, Head, Section on Medical Neuroendocrinology, NICHD
  • Marissa Lightbourne, MD, Staff Clinician
  • Mohammad Al-Jundi, MD, Clinical Fellow
  • Iris Hartley, MD, Clinical Fellow
  • Rasha Haykal, MD, Clinical Fellow
  • Crystal Kamilaris, MD, Clinical Fellow
  • Maziar Rahmani, MD, PhD, Clinical Fellow
  • Skand Shekar, MD, Clinical Fellow

The Inter-Institute Endocrinology Training Program (IETP) is a three-year training program that seeks to train internal medicine physicians to become first-rate endocrinologists dedicated to investigative careers. The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), the National Institute of Child Health and Human Development (NICHD), and the National Institute of Dental and Craniofacial Research (NIDCR) participate in the program, with faculty from all three institutes.

Clinical and research training

Clinical training occurs largely in the first year. At any one time, fellows are responsible for five to ten patients on the inpatient service of the NIH. Under the supervision of the endocrine faculty, the trainee has complete responsibility for all aspects of a patient’s care. Fellows make daily rounds, discuss patients with the attending physicians, and participate in management decisions related to both patient care and clinical investigation. Although all patients are admitted under peer-reviewed research protocols, there are many other aspects of diagnosis and patient care that fall entirely under the discretion of the endocrine fellows.

Developing an independent career as a physician scientist is the primary focus during the second and third years of training; emphasis is placed on how to develop research questions and hypothesis-driven research protocols. To this end, the second and third years are spent primarily in the laboratory or conducting clinical research under the mentorship of a senior investigator in one of the several endocrinology branches of the NIH. During this research period, fellows continue to gain active clinical experience through bi-weekly continuity outpatient clinics (general endocrinology as well as diabetes clinics) and by participating in clinical conferences. In addition, fellows on the endocrine service serve as consultants to other services within the Clinical Center, where patients are not selected with regard to endocrine problems. Thus, fellows gain experience with the several common endocrine problems that may occur in any general medical ward. Clinical research activities include programs in all the areas of endocrine and metabolic disease. Study design, outcome measures, statistical analysis, and ethical and regulatory issues are stressed.

The IETP provides a comprehensive training experience that involves not only the NIH clinical branches working in endocrinology but also Georgetown University Hospital, Washington Hospital Center, and Walter Reed Medical Center. The basic and clinical endocrine research facilities at the NIH are among the most extensive and highly regarded in the world. Thus, the fellowship is ideal for physicians who seek a broad education in both research and clinical endocrinology.


  1. Kamilaris CDC, Stratakis CA. Multiple endocrine neoplasia type 1 (MEN1): an update and the significance of early genetic and clinical diagnosis. Front Endocrinol (Lausanne) 2019;10:339.
  2. Hartley IR, Costa Beber Nunes J, Lodish M, Stratakis CA. Cushing disease in a patient with nonbullous congenital ichthyosiform erythroderma: lessons in avoiding glucocorticoids in ichthyosis. J Pediatr Endocrinol Metab 2019;32(8):911-914.
  3. Hartley I, Zhadina M, Collins MT, Boyce AM. Fibrous dysplasia of bone and McCune-Albright syndrome: a bench to bedside review. Calcif Tissue Int 2019;104(5):517-529.
  4. Kamilaris CDC, Faucz FR, Voutetakis A, Stratakis CA. Carney complex. Exp Clin Endocrinol Diabetes 2019;127(2-03):156-164.
  5. Kushchayeva Y, Lightbourne M, Lodish M, Stratakis CA. Genetic tumor syndromes with endocrine involvement: a compendium and an update. Pediatr Endocrinol Rev 2019;16(3):311-334.


  • Kenneth Berman, MD, Director, Endocrine Training Program, Washington Hospital Center, Washington, DC
  • Rebecca Brown, MD, Diabetes, Endocrinology, and Obesity Branch, NIDDK, Bethesda, MD
  • Alan H. DeCherney, MD, Reproductive Endocrinology and Infertility Training Program, NICHD, Bethesda, MD
  • Rachel Gafni, MD, Craniofacial and Skeletal Diseases Branch, NIDCR, Bethesda, MD
  • Phillip Gorden, MD, Diabetes, Endocrinology, and Obesity Branch, NIDDK, Bethesda, MD
  • James C. Reynolds, MD, Nuclear Medicine Department, NIH Clinical Center, Bethesda, MD
  • William F. Simonds, MD, Metabolic Diseases Branch, NIDDK, Bethesda, MD
  • Joseph Verbalis, MD, Director, Endocrine Training Program, Georgetown University Medical Center, Washington, DC
  • Lee S. Weinstein, MD, Metabolic Diseases Branch, NIDDK, Bethesda, MD


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