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National Institutes of Health

Eunice Kennedy Shriver National Institute of Child Health and Human Development

2015 Annual Report of the Division of Intramural Research

Maternal-Fetal Medicine Fellowship Training Program

The goal of the Fellowship is to train individuals to provide specialized patient care in Maternal-Fetal Medicine as well as to prepare candidates for a career in academic medicine as physician scientists. It is a three-year training program. There is the possibility of completing a combined Maternal-Fetal Medicine and Human Genetics Fellowship, and candidates can opt to complete a PhD, which is based in the Department of Physiology at Wayne State University.

The clinical rotations (18 months) include: maternal-fetal medicine or high-risk obstetric service, obstetrical ultrasound, reproductive genetics, labor and delivery, anesthesia/intensive care unit, fetal echocardiography, and elective rotations. The program is housed at Hutzel Women’s Hospital (with 5,000 deliveries per year), Detroit, and Faculty Members are Wayne State University appointees as well as Attendings of the Detroit Medical Center. The Perinatology Research Branch (PRB) is also housed at the Detroit Medical Center in Detroit, MI. The program is approved for seven positions, two of which are funded by the Perinatology Research Branch and the remainder by the Detroit Medical Center. The Fellowship emphasizes clinical, translational, and basic research (18 months are dedicated to research). Ideal candidates for our Program are well trained individuals from a university program wishing to pursue a career in academic medicine, who thrive in a rigorous and challenging environment and are goal-oriented and self-motivated.

The Fellowship emphasizes a multi-disciplinary approach to complications of pregnancy. There is a strong emphasis on the prenatal diagnosis of congenital anomalies with ultrasound, and our graduates are expected to be proficient in two-dimensional and three-dimensional ultrasound, fetal echocardiography, advanced imaging techniques such as Doppler, as well as ultrasound-guided invasive procedures such as amniocentesis. Opportunities for laboratory-based research and training are available in the fields of parturition, reproductive immunology, placental pathology and biology, biomarker discovery, and systems biology in reproduction, which are Units related to the Perinatology Research Branch. Alternative opportunities are available at the C.S. Mott Center of Wayne State University.

Primary areas of interest of the PRB are the mechanisms responsible for obstetrical disease, prediction and prevention of preterm birth, prenatal diagnosis of congenital anomalies, the role of infection and inflammation in perinatal disease, fetal growth and development, placental pathology, and the use of high-dimensional biology techniques to identify biomarkers for preterm labor, preterm PROM (premature rupture of membranes), preeclampsia, fetal death, and IUGR (intrauterine growth restriction).

Detailed information about the training program is available at the following website: The website contains information about each current fellow (as well as the faculty) and his/her publications and awards. The Director of the Fellowship is Dr. Lami Yeo, and the Associate Director for the PRB is Dr. Roberto Romero, Chief of the Perinatology Research Branch and Head of the Program in Perinatal Research and Obstetrics. The Program is sponsored by the Perinatology Research Branch, Detroit Medical Center, and Wayne State University. Fellows are employees of the Detroit Medical Center (DMC), and program oversight is with the Office of Graduate Medical Education of the DMC.


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